The zoo is an accredited member of the Association of Zoos and Aquariums (AZA), and a member of the World Association of Zoos and Aquariums (WAZA). The zoo is known for being the home of Martha, the last living passenger pigeon, and to Incas, the last living Carolina parakeet. In 1986, the Lindner Center for Conservation and Research of Endangered Wildlife (CREW) was created to further the zoo's goal of conservation.

In addition, the zoo also has conducted several breeding programs in its history, and was the first to successfully breed California sea lions.

The zoo houses over 500 species, 1,800 animals and 3,000 plant species. It was appointed as a National Historic Landmark in 1987. It originally began with 64.5 acres (26.1 ha) in the middle of the city, but has spread into the neighboring blocks and several reserves in Cincinnati's outer suburbs.

It is located in the Avondale neighborhood of Cincinnati, Ohio. The Cincinnati Zoo & Botanical Garden is the sixth oldest zoo in the United States, founded in 1873 and officially opening in 1875.

Longest breeding time in dragon city